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| 722 BC |
| | | The Assyrians overwhelm the north of Israel and the ten northern tribes vanish from history - the majority of them probably dispersed or sold into slavery | |
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| 416 BC |
| | | The Athenians, capturing Melos, kill all the males of the island and sell the women and children into slavery | |
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| c. 700 |
| | | The African slave trade through the Sahara is so extensive that a new town, Zawila, is established as a trading station | |
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| c. 850 |
| | | The caliphs in Baghdad begin to employ Turkish slaves, or Mamelukes, in their armies | |
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| 1446 |
| | | Portugal claims ownership of the region of Guinea, subsequently the centre of their slave trade on the west African coast | |
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| 1466 |
| | | The Portuguese settlers on the Cape Verde islands are granted a monopoly on the new slave trade | |
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| c. 1550 |
| | | Africans, bought in the Portuguese trading posts of west Africa, are shipped across the Atlantic as slaves | |
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| 1655 |
| | | The British, settling in Jamaica, soon turn the island into the major slave market of the West Indies | |
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| 1657 |
| | | The Dutch in South Africa purchase slaves to do domestic and agricultural work | |
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| 1688 |
| | | Aphra Behn's novel Oroonoko makes an early protest against the inhumanity of the African slave trade | |
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